Atypical Clinical Course of the Acute Myocardial Infarction: Clinical and Anamnestic Characteristic of Patients, Management and Outcomes (Data From Registry of Acute Myocardial Infarction)

Aim. To study clinical and anamnestic specifics, management and outcomes of acute myocardial infarction (MI) in patients with atypical clinical presentation. Material and methods. Among the Tomsk population, those having had acute MI in 2009-2014 y. were included, registered in the database “Registry of Acute MI” (n=5602), and selected to groups with atypical (n=1319) and common (n=4283) clinical presentation of the MI onset. Statistics was done with software “Statistica 10”. Results. Atypical presentation of MI took place in 23,5% cases. These patients were much older than those with common angina at MI onset; they had more prevalent arterial hypertension, obesity, diabetes. Also, the prevalence of anamnestic MI did not differ between groups, however autopsy revealed more common painless MI. Atypical MI presentation patients sought for medical care in 28 days before the event of MI more frequently than those with typical clinical picture: 36% vs. 26% (p<0,001), but electrocardiography was ordered only for a half of them (54%), that led to misdiagnostics of pre-infarction condition. Every second patient with atypical MI was hospitalized to non-specialized unit, where could not receive high-technology treatment, which hence led to worse outcomes and prognosis. Conclusion. It is necessary to be careful with non-typical MI development possibility in older patients with several comorbidities, and with anamnesis of painless acute MI. Chance of fatal outcome in atypical MI is 10 times higher in this group than in those with typical clinical presentation.