Use of Chlorpromazine and Reserpine in the Treatment of Emotional Disorders

• Patients receiving uninterrupted medication with either chlorpromazine or reserpine constituted a control group for comparison with a group in whom the medication was interrupted by one month of medication with a placebo. Both chlorpromazine and reserpine caused significant behavioral and affective improvement, especially in the manic phase of manic-depressive psychosis, in agitated states, and in schizophrenic reaction. The drugs differed in their side-effects, but they are valuable to the psychiatrist in controlling destructive, disturbed behavior regardless of the underlying etiology.