This study compared seven different mathematical methods for calculating mean platelet survival time in normal subjects.
Method selection for platelet survival calculations warrants caution; leaves open the optimal approach for clinical or research use.
The International Committee of Standardization in Haematology has recommended in 1977 three methods for calculating the mean platelet survival time of isotope labelled platelets, although in recent years other mathematical equations were also suggested for the determination of platelet survival times. Seven different methods of calculating the mean survival time for normals were investigated and were compared with one another.
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Strydom et al. (1987) studied this question.
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