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January 1, 1988The Journal of AntibioticsOpen Access

Novel antifungal antibiotics octacosamicins A and B. I. Taxonomy, fermentation and isolation, physico-chemical properties and biological activities.

Kazuyuki Dobashi Naoko Matsuda MASA HAMADA HIROSHI NAGANAWA TOMOHISA TAKITA TOMIO TAKEUCHI

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Abstract

Two antifungal antibiotics octacosamicins A and B were isolated from the culture broth of a strain of actinomycetes, which was identified as a strain of Amycolatopsis. These antibiotics were isolated by resin adsorption and purified by column chromatography and preparative HPLC. Both antibiotics were found to be new substances from their physico-chemical properties. They showed broad antifungal spectra.

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Dobashi et al. (1988) studied this question.

synapsesocial.com/papers/6a98d28d7a0bd180b0e10bcc https://doi.org/10.7164/antibiotics.41.1525

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