Gastro-oesophageal reflux and asthma; a common association, but of what clinical importance?

Gastro-oesophageal reflux and asthma; a common association, but of what clinical importance? effect on the antireflux barrier and further promote gastro- oesophageal reflux. Experimental work, however, has shown that maximum inspiratory efforts in normal subjects can produce transdiaphragmatic pressures of 300 cm H20 with- out causing gastro-oesophageal reflux. In asthmatic patients on July 14, 2023 by guest.