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The effect of ethyl alcohol on the splanchnic or liver blood flow has been a matter of 'debate. According to earlier investigations [Starling (1)] ethanol has little effect on the cardiovascular system, its influence being mainly confined to a dilatation of the vessels of the skin and of the mucous membranes. The investigation of Smythe, Heinemann and Bradley on dogs (2) supported this concept. However, Mendeloff (3) in studies on man observed a striking increase in the splanchnic blood flow during intravenous infusions of ethyl alcohol. In this laboratory, metabolism of ethanol is now being studied. During these studies no effect of ethanol on the splanchnic blood flow could be found. The aim of this paper is to present these data.
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Castenfors et al. (1960) studied this question.
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