Key result
Surgery for acute left-sided infective endocarditis had higher rates of low cardiac output syndrome (13.3% vs 4.8%) but comparable long-term quality of life compared to non-IE cardiac surgery.
Why the study?
Surgery for left-sided infective endocarditis improves survival, but data regarding quality of life after surgery remain scarce.
Does cardiac surgery for acute left-sided infective endocarditis result in different quality of life compared to cardiac surgery for non-endocarditis indications in adult patients?
Cohort (n=105)
Does cardiac surgery for acute left-sided infective endocarditis result in different quality of life compared to cardiac surgery for non-endocarditis indications in adult patients?
Survivors of surgery for acute left-sided infective endocarditis achieve a quality of life comparable to patients undergoing cardiac surgery for other indications, despite a higher initial risk profile and more postoperative complications.
IE surgery survivors incur more perioperative complications yet report comparable long-term QoL; leaves open generalizability and role in decision-making.
Surgery for left-sided infective endocarditis (IE) has been demonstrated to improve patients’ survival rates but information about quality of life (QoL) after surgery is scarce. The aim of this study was to assess the postoperative outcomes and QoL after surgery for IE patients compared to patients undergoing cardiac surgery for non-IE indications. Adult patients with definite acute left-sided IE were matched 1:1 to patients who underwent cardiac surgery for non-endocarditic purposes from 2014 to 2019. QoL was assessed using the SF-36 survey at the last follow-up. A total of 105 patients were matched. The IE group had higher rates of preoperative stroke (21% vs. 7.6%, p = 0.005) and higher stages of NYHA class (p < 0.001), EuroSCORE II (12.3 vs. 3.0, p < 0.001) and blood cell count abnormalities (p < 0.001). The IE group had higher incidence of low cardiac output syndrome (13.3% vs. 4.8%, p = 0.029), dialysis (10.5% vs 1.0%, p = 0.007) and prolonged mechanical ventilation (16.2% vs. 2.9%, p = 0.002) after surgery. At the last follow-up, subcomponents of the SF-36 QoL survey were not different between the groups. Patients who underwent cardiac surgery for IE demonstrated a higher risk profile with a higher rate of postoperative complications. Once recovered from the acute phase of the disease, the reported QoL at follow-up was comparable to that of matched cardiac patients operated for non-IE purposes.
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Fernández‐Cisneros et al. (2023) conducted a cohort in Acute left-sided infective endocarditis (n=105). Surgery for acute left-sided infective endocarditis vs. Cardiac surgery for non-endocarditic purposes was evaluated on Quality of life (QoL) assessed using the SF-36 survey at the last follow-up. Surgery for acute left-sided infective endocarditis had higher rates of low cardiac output syndrome (13.3% vs 4.8%) but comparable long-term quality of life compared to non-IE cardiac surgery.
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