What question did this study set out to answer?

Document and characterize a case of atypical neuroleptic malignant syndrome developing in association with long-acting injectable paliperidone therapy.

April 19, 2016Journal of Clinical Psychopharmacology

Atypical Neuroleptic Malignant Syndrome Associated With Paliperidone Long-Acting Injection

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Key result

Paliperidone long-acting injection is associated with the development of atypical neuroleptic malignant syndrome.

Key Points

Document and characterize a case of atypical neuroleptic malignant syndrome developing in association with long-acting injectable paliperidone therapy.
Clinical evaluation and case presentation of an adverse reaction following administration of paliperidone long-acting injection.
Atypical neuroleptic malignant syndrome presented with non-classic clinical features following administration of long-acting injectable paliperidone.
Sustained medication release from depot formulations prolonged the monitoring and management period required for clinical recovery.

Implication

May warrant vigilance for atypical NMS with paliperidone LAI; hypothesis-generating and needs prospective confirmation.

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Cite This Study

Langley-DeGroot et al. (2016) studied this question. Paliperidone long-acting injection is associated with the development of atypical neuroleptic malignant syndrome.

synapsesocial.com/papers/6a98de508274c2559e362149 https://doi.org/10.1097/jcp.0000000000000507

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Atypical Neuroleptic Malignant Syndrome Associated With Paliperidone Long-Acting Injection

Key Points

Implication

Discussion

Cite This Study

Atypical Neuroleptic Malignant Syndrome Associated With Paliperidone Long-Acting Injection

Key Points

Implication

Discussion

Cite This Study

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