Key result
Two cases of primary right atrial angiosarcoma demonstrate the aggressive nature of the tumor and the use of multimodality treatment including surgery and chemotherapy.
Why the study?
Cardiac angiosarcomas are rare malignant tumors with poor survival outcomes, and current treatments often yield limited results with local relapse or metastatic recurrence.
Case Report (n=2)
No
This case report describes the clinical course of two patients with rare primary cardiac angiosarcoma in the right atrium, emphasizing the poor survival outcomes and limited treatment efficacy.
Current treatments show limited results in right atrial angiosarcoma; leaves open the need for novel therapeutic research in this rare entity.
Cardiac angiosarcomas are rare malignant tumors, predominantly affecting the right heart with poor survival outcomes. The current mainstay of treatment consists of surgery with or without chemotherapy, but often yields limited results with local relapse or metastatic recurrence. This case report describes 2 patients with primary angiosarcoma located in the right atrium. One patient received neo-adjuvant and adjuvant chemotherapy; both were scheduled for surgical resection. The course of disease is described followed by a comprehensive review of the literature.
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Vanderheyden et al. (2020) conducted a case report in Primary cardiac angiosarcoma (n=2). Surgical resection and chemotherapy was evaluated. Two cases of primary right atrial angiosarcoma demonstrate the aggressive nature of the tumor and the use of multimodality treatment including surgery and chemotherapy.
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