Key result
Pediatric upper extremity postthrombotic syndrome frequency varied by pathogenesis and age, occurring in 87% of primary cases, 16% of secondary neonates, and 49% of secondary non-neonates (P<0.0001).
Population
158 children with objectively confirmed upper extremity deep vein thrombosis, categorized into primary…
Design
Cohort
Authors
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May inform PTS surveillance by DVT pathogenesis and age in children; hypothesis-generating and requires prospective confirmation.
Cohort (n=158)
p-value: p=<.0001
Pediatric upper extremity postthrombotic syndrome frequency and severity depend on DVT pathogenesis and patient age, with line-related DVT having a more benign course, especially in neonates.
Avila et al. (2014) conducted a cohort in Upper extremity deep vein thrombosis (n=158). Upper extremity deep vein thrombosis pathogenesis (primary vs secondary) vs. Comparison among primary, secondary neonates, and secondary non-neonates was evaluated on Time to PTS score ≥1 (Modified Villalta Scale) (p=<.0001). Pediatric upper extremity postthrombotic syndrome frequency varied by pathogenesis and age, occurring in 87% of primary cases, 16% of secondary neonates, and 49% of secondary non-neonates (P<0.0001).