Bionanomanipulation Using Atomic Force Microscopy

This paper explains how an AFM-based nanorobot was developed to visualize and quantify the dynamics of cell proteins interactions under physiological and pathophysiological conditions at the nanoscale. As these events are directly related at the molecular level to the causes of many life-threatening or incurable diseases, the development of an AFM-based nanorobot, which can image and manipulate biological objects at the single molecule level, is a novel approach to reveal disease markers and elucidate the disease mechanisms.