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The effect of a Bi2 deficiency on transmethylation from methionine to choline has been studied. The deficiency did not influence the level of choline in the liver nor the excretion of urinary choline. Histological examination of livers and kidneys did not reveal the fatty infiltration or renal damage characteristic of a choline deficiency. From this study it appears that vit. Bi2 is not involved in this direct transmethylation.
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Firth et al. (1954) studied this question.
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