Achillea millefolium L. (yarrow) from Bulgaria was extracted in a supercritical pilotscale plant using carbon dioxide (CO2). First, the extraction yield was studied as a function of time at 14 MPa, 40 C and 70 g/min of CO2. Then, the extraction time was set in order to study the effect of different process parameters (pressure, temperature, CO2 flow and use of ethanol as co-solvent) on the extraction yield. The composition of the volatile oil obtained in yarrow extracts was thoroughly studied by GC-MS.
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Villanueva-Bermejo et al. (2016) studied this question.
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