This review explores contributions in asymmetric organocatalysis from the patent literature since 2018, including reactions catalyzed by Cinchona alkaloids as free base and quaternary salts, phosphonium salts, proline-derived catalysts, and chiral phosphoric acids. Examples of processes employing asymmetric organocatalysis for the industrial preparation of pharmaceutical intermediates are highlighted.
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David L. Hughes (2022) studied this question.
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