Sodium 1-(12-hydroxy)octadecanyl sulfate (1) was isolated from a marine tunicate as a matrix metalloproteinase 2 (MMP2) inhibitor.(1) The structure was elucidated by a combination of spectroscopic and chemical methods. Compound 1 inhibited MMP2 with an IC(50) value of 9.0 microg/mL.
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Fujita et al. (2002) studied this question.
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