[reaction: see text] A new class of cyclohexane-based P,N-ligands is readily obtained through aziridine ring opening with suitable phosphorus nucleophiles under acidic conditions. trans-1-Amino-2-diphenylphosphinocyclohexane is resolved with tartaric acid to give the final product in >99% ee. The new ligands show high stability toward oxidation at the phosphorus atom.
No takes yet. Share an insight, caveat, or question.
Caiazzo et al. (2002) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: