Key result
At 5 years, TRansluminal Occlusion of Perforator (TRLOP) for incompetent perforator veins achieved an 81% closure rate (101 of 125 veins analyzed).
Why the study?
Does ultrasound-guided radiofrequency ablation (TRLOP) maintain closure of incompetent perforator veins at 5 years?
Observational (n=37)
Single-blind
Does ultrasound-guided radiofrequency ablation (TRLOP) maintain closure of incompetent perforator veins at 5 years?
Ultrasound-guided radiofrequency ablation (TRLOP) for incompetent perforator veins demonstrates an 81% closure rate at 5 years, comparable to subfascial endoscopic perforator surgery.
May support TRLOP durability in perforator disease; leaves open randomized comparison to surgery.
UNLABELLED: In 2000, we developed a percutaneous method of treating incompetent perforator veins (IPV) using ultrasound-guided radiofrequency ablation (RFA), which we termed TRansluminal Occlusion of Perforator (TRLOP). OBJECTIVE: To audit the five-year outcome of the TRLOP technique as indicated by the rate of IPV closure on duplex ultrasound (DUS). METHODS: Patients underwent DUS five years post-TRLOP. Experienced vascular technologists documented the presence of IPVs using a two co-ordinate system, blinded to previous results. Results were then compared with preoperative scans. IPVs were classified as: closed; not closed/reopened; or de novo. Closed IPVs were defined as the absence of any IPV at or within 5 cm of a previous IPV in the vertical and horizontal plane. Any IPVs found outside the delineated area were defined as de novo IPVs. RESULTS: Of 67 patients invited, 37 attended DUS (55% participation rate; men to women ratio of 14:23, age 40-84; mean 64). Preoperative clinical, aetiological, anatomical and pathological classification: C2, 36.2%; C3, 27.6%; C4, 34.5%; C6, 1.7%. From 125 IPVs analysed, 101 were closed (81%), 24 were not closed/reopened (19%) and 14 de novo IPVs were found. DISCUSSION: Despite these results representing our learning curve for the procedure, we found TRLOP to be an effective treatment for IPVs. The closure rates described are comparable with the published clinical series data for subfascial endoscopic perforator surgery.
No takes yet. Share an insight, caveat, or question.
Bacon et al. (2009) conducted an observational in Incompetent perforator veins (n=37). TRansluminal Occlusion of Perforator (TRLOP) was evaluated on Rate of IPV closure on duplex ultrasound (DUS). At 5 years, TRansluminal Occlusion of Perforator (TRLOP) for incompetent perforator veins achieved an 81% closure rate (101 of 125 veins analyzed).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: