Effect of D-Sorbitol on Absorption of Vitamin B12 by Pernicious Anemia Patients.

This is the authors' abstract. We don't add key points for this paper.

1) In the urinary excretion test 5 pernicious anemia patients excreted radioactivity corresponding to an average of 0.02 μg of Vit. B12 when fed 2 μg of Vit. B12 orally and excreted an average of 0.02 μg when fed 2 μg of Vit. B12 together with 0.1 to 10 g of sorbitol. These patients excreted an average of 0.23 μg when fed 2 μg of Vit. B12 with intrinsic factor and an average of 0.22 μg when 2 μg of Vit. B12 were fed together with intrinsic factor and 10 g of sorbitol. 2) These 5 anemia patients excreted an average of 0.29 μg when fed 30 μg of Vit. B12 and 0.12 μg when fed 30 μg of Vit. B12 together with 10 to 21 g of sorbitol. The same 5 patients excreted an average of 0.35 μg when fed 30 μg of Vit. B12 with intrinsic factor, and excreted 0.33 μg when 10 to 21 g of sorbitol was fed together with 30 μg of Vit. B12 and intrinsic factor. 3) Sorbitol had no effect in promoting absorption of Vit. B12 in pernicious anemia patients.