Changing Concepts in the Management of Severe Ocular Surface Disease Over Twenty-five Years

From the University of Cincinnati and Cincinnati Eye Institute (E.J.H.), Cincinnati, Ohio; and the University of Minnesota, and Associated Eye Care, Saint Paul, Minnesota, U.S.A. Submitted February 2, 2000. Accepted April 30, 2000. Address correspondence and reprint requests to Dr. E.J. Holland, Clinical Professor of Ophthalmology, Cincinnati Eye Institute, 10494 Montgomery Road, Cincinnati, OH 45242, U.S.A.