Key result
Peri- and partial epicardiectomy completely restored clinical and biochemical liver parameters and resolved ascites and pleural effusions at 2-year follow-up in a patient with cardiac cirrhosis.
Case Report (n=1)
Constrictive pericarditis is a rare, reversible cause of cardiac cirrhosis that can be cured by pericardiectomy, highlighting the importance of cardiac evaluation in unexplained liver cirrhosis.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for pericardiectomy in cardiac cirrhosis; prospective studies needed before clinical adoption.
Constrictive pericarditis usually leads to heart failure but can also cause extra cardiacdiseases. We report a patient who presented with dyspnea, recurrent pericardial and pleural effusions as well as ascites. An initial cardiologic examination revealed a pericardial effusion without severe hemodynamic impairment, but without signs of additional pathologies. Abdominal sonography showed liver cirrhosis, which was laboratory classified as Child grade B. The patient was referred to a transplantation center for liver transplant evaluation. During the liver transplant evaluation process, Cardiac Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) finally revealed a constrictive non-calcifying pericarditis as the origin of the cardiac cirrhosis and the patient was scheduled for periand partial epicardiectomy. Two years later, clinical and biochemical liver parameters were completely restored. There was no recurrence of ascites or pleural effusions. At follow-up, cardiac CT and MRI proved the absence of a pericardial constriction while liver sonography showed normal hepatic morphology. This case presents a highly rare cause for liver cirrhosis and underlines the importance of a complete cardiac evaluation in case of a present liver cirrhosis of unknown causes.
No takes yet. Share an insight, caveat, or question.
A 2013 study conducted a case report in Constrictive, non-calcifying pericarditis causing cardiac cirrhosis (n=1). Peri- and partial epicardiectomy was evaluated on Clinical and biochemical liver parameters, recurrence of ascites/effusions, and cardiac/hepatic morphology. Peri- and partial epicardiectomy completely restored clinical and biochemical liver parameters and resolved ascites and pleural effusions at 2-year follow-up in a patient with cardiac cirrhosis.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: