SUMMARY. A man aged 22, exposed to 9‐bromofluorene developed an extensive bullous eruption. A patch test with pure 9‐bromofluorene in a healthy subject not previously exposed to this substance provoked a mild and transient reaction at 24 hr., but a severe reaction 9–10 days later. The delayed reaction was characterized histologically by intense epidermal hyperplasia, pseudoepitheliomatous in degree, and a dense cellular infiltrate in the upper dermis. These effects are discussed in relation to the reactions normally obtained in contact hypersensitivity.
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E. W. Powell (1968) studied this question.
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