Answers are grounded in this paper and cite their sources.
Meperidine hydrochloride is the most commonly prescribed opioid analgesic for postoperative pain in our hospital. Biotransformation of meperidine may lead to a potentially toxic metabolite, normeperidine. We describe two cases of apparent normeperidine toxicity and discuss reasons for normeperidine accumulation.
No takes yet. Share an insight, caveat, or question.
Armstrong et al. (1986) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: