A Case of Sino-nasal Inverted Papilloma Arising in the Bilateral Nasal Cavity and Containing a Malignant Tumor

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Inverted papilloma of the nasal cavity and paranasal sinuses is characterized clinically by a high local recurrence rate and possibility of containing a malignant tumor. It normally arises and grows on only one side of the nose, and independent occurrence on both sides is very rare.We report a case of sino-nasal papillomas that arose independently on both sides, each of which contained a malignant tumor. The patient was a 59-year-old man who came to our hospital complaining of nasal obstruction of two months duration on both sides. Based on the results of a CT examination he was diagnosed with chronic sinusitis and nasal polyps, and endoscopic sinus surgery (ESS) was performed. Histological examination revealed an inverted papilloma on both sides, each of which contained a squamous cell carcinoma. Additional surgery to completely remove the lesions consisted of lateral rhinotomy on the right side and ESS on the left. Following the three surgical procedures to remove the tumors, maximum-dose radiotherapy was administered. The patient's postoperative course has been uneventful with no recurrence of the tumors as of ten months post operatively.