BACKGROUND: Conventional therapeutic agents used for treatment of Acne are associated with various adverse effects necessitating development of safe and effective alternative therapeutic agents. In this context, a polyherbal formulation AHPL/AYCAP/0413 was developed for treatment of Acne. OBJECTIVES: To evaluate Anti-inflammatory and antimicrobial activity of AHPL/AYCAP/0413. MATERIAL AND METHODS: were incubated under aerobic conditions at 37°C. TSB with glucose agar was used as the agar base. 0.5ml of formulation and clindamycin (10 μg/ml) were introduced in to the wells randomly. The antibacterial activity was evaluated by measuring zones of inhibition (in mm). RESULT: , S. epidermidis and S. aureus respectively. This activity was also comparable to that of Clindamycin. CONCLUSION: AHPL/AYCAP/0413 capsule possesses significant Anti-inflammatory and Anti-microbial activities which further justifies its role in the management of Acne vulgaris. SUMMARY: : Staphylococcus aureus.
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Nipanikar et al. (2017) studied this question.