Answers are grounded in this paper and cite their sources.
A novel approach for the synthesis of omeprazole, a potent antiulcer drug, is described. The synthetic procedure involved the formation of an ester of the 5-methoxy thiobenzimidazole followed by coupling of the ester with the Grignard reagent of 2-chloromethyl-4-methoxy-3,5-dimethyl-pyridine.
No takes yet. Share an insight, caveat, or question.
Bhalerao et al. (2010) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: