Pituitary Myxedema: Report of Three Cases

Article1 January 1950PITUITARY MYXEDEMA: REPORT OF THREE CASESH. ST. GEORGE TUCKER JR., M.D., JAMES L. CHITWOOD, M.D., CARL P. PARKER JR., M.D.H. ST. GEORGE TUCKER JR., M.D.Search for more papers by this author, JAMES L. CHITWOOD, M.D.Search for more papers by this author, CARL P. PARKER JR., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-32-1-52 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1940 Means, Hertz and Lerman1 described a group of patients with myxedema who did not respond well to thyroid treatment. When the usual doses of desiccated thyroid were given, the patients became weaker, and in some the picture of adrenal insufficiency developed. It was shown that in these patients myxedema was only part of a more widespread glandular failure resulting from primary insufficiency of the anterior pituitary gland. The name "pituitary myxedema" was suggested for this condition. Similar cases have been reported by other authors.2-8Pituitary myxedema may be regarded as a special type of anterior pituitary failure or...Bibliography1. MeansHertzLerman JHSJ: The pituitary type of myxedema, or Simmonds' disease masquerading as myxedema, Tr. A. Am. Physicians 55: 32-53, 1940. Google Scholar2. LermanStebbins JHD: The pituitary type of myxedema, J. A. M. A. 119: 391-395, 1942. CrossrefGoogle Scholar3. Dunn CW: Pituitary myxedema, M. Clin. North America 28: 1386-1405, 1944. CrossrefGoogle Scholar4. Welty DM: The pituitary type of myxedema, M. Bull. Vet. Adm. 21: 89-91, 1944. Google Scholar5. Swartz H: Slow-growing hypophyseal tumor associated with hypothyroidism—a case report, New York State J. Med. 45: 1683-1684, 1945. Google Scholar6. CluxtonBennettKepler HEWAEJ: Anterior pituitary insufficiency (panhypopituitarism-Simmonds' disease), pituitary myxedema and congestive heart failure (myxedema heart); report of a case and findings at necropsy, Ann. Int. Med. 29: 732-745, 1948. LinkGoogle Scholar7. WilliamsWhittenberger RHJL: Treatment of Simmonds' disease, J. Clin. Endocrinol. 2: 539-550, 1942. CrossrefGoogle Scholar8. FraserSmith RPH: Simmonds' disease or panhypopituitarism (anterior). Its clinical diagnosis by the combined use of two objective tests, Quart. J. Med. 10: 297-330, 1941. Google Scholar9. Sheehan HL: Post-partum necrosis of the anterior pituitary, J. Path. and Bact. 45: 189-214, 1937. CrossrefGoogle Scholar10. FraserAlbrightSmith RFPH: The value of the glucose-tolerance test, the insulin tolerance test, and the glucose-insulin tolerance test in the diagnosis of endocrinologic disorders of glucose metabolism, J. Clin. Endocrinol. 1: 297-306, 1941. CrossrefGoogle Scholar11. RobinsonPowerKepler FJMHEJ: Two new procedures to assist in the recognition and exclusion of Addison's disease. A preliminary report, Proc. Staff Meet., Mayo Clin. 16: 577-583, 1941. Google Scholar12. Means JH: The thyroid and its diseases, second edition, 1948, J. B. Lippincott Co., Philadelphia, p. 230. Google Scholar13. Selye H: The general adaptation syndrome and the diseases of adaptation, J. Clin. Endocrinol. 6: 117-230, 1946. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication January 13, 1948.From the Medical Service, McGuire Veterans Administration Hospital and the Department of Medicine, Medical College of Virginia Hospital, Richmond, Virginia.Published with permission of the Chief Medical Director, Department of Medicine and Surgery, Veterans Administration, who assumes no responsibility for the opinions expressed or conclusions drawn by the author. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIntravitale Trypanblau-Speicherung in den Epithelzellen des proximalen Nierentubulus nach Sublimat-Intoxikation und anschlie�ender L-Thyroxin-BehandlungAcute renal failure influenced by administration of thyroid hormoneDas Herz bei Myxödem und HypothyreoseHYPONATREMIA IN PRIMARY MYXEDEMA*ROBERT H. CURTIS, M.D.Krankheiten der SchilddrüseVegetatives System 1 January 1950Volume 32, Issue 1Page: 52-62KeywordsHospital medicineMedical servicesPituitary glandSurgeryThyroid ePublished: 1 December 2008 Issue Published: 1 January 1950 PDF downloadLoading ...