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November 25, 2009Blood

Expression of terminal α2-6–linked sialic acid on von Willebrand factor specifically enhances proteolysis by ADAMTS13

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RMRachel T. McGrathRoyal North Shore HospitalTMThomas A. J. McKinnonImperial College LondonBBBarry J. ByrnePediatric Cardiology

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McGrath et al. (2009) studied this question.

synapsesocial.com/papers/6a992e70ea739e5cccf5b1cbhttps://doi.org/10.1182/blood-2009-09-241547
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  2. 2Carbohydrate moiety of von Willebrand factor is not necessary for maintaining multimeric structure and ristocetin cofactor activity but protects from proteolytic degradation.1984 · 83 citations
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