Educational Case: From pleural tap to diagnosis: An educational journey in the pathology of mesothelioma

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Occupational and environmental exposures can produce specific pathologic changes in affected organs, such as the development of mesothelioma from chronic exposure. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

Luke Passannante; Samer Khader; Laleh Hakima

doi:10.1016/j.acpath.2026.100288

September 1, 2026Academic PathologyOpen Access

Educational Case: From pleural tap to diagnosis: An educational journey in the pathology of mesothelioma

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Key Points

Illustrate the diagnostic workflow for identifying mesothelioma through pleural tap analysis while exploring how chronic occupational and environmental exposures induce tissue pathology.
Presented an educational pathology case tracking clinical assessment from initial pleural fluid aspiration to microscopic tissue diagnosis.
Mapped common industrial, occupational, and environmental agents to chronic pathological changes in primary target organ systems.
Demonstrates the step-by-step diagnostic cytopathology required to identify malignant pleural mesothelioma secondary to chronic hazardous inhalation.
Identifies the pulmonary and pleural organ systems as primary targets of structural and cellular damage resulting from chronic mineral and industrial exposures.

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Implication

Educational case report demonstrates the diagnostic pathology of mesothelioma following occupational exposure, highlighting the role of pleural fluid analysis in clinical evaluation.

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Cite This Study

Passannante et al. (2026) studied this question.

synapsesocial.com/papers/6a99355b636c6408cfa7d7c6 https://doi.org/10.1016/j.acpath.2026.100288

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Educational Case: From pleural tap to diagnosis: An educational journey in the pathology of mesothelioma

Key Points

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Implication

Abstract

Discussion

Cite This Study

Educational Case: From pleural tap to diagnosis: An educational journey in the pathology of mesothelioma

Key Points

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Implication

Abstract

Discussion

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