Experimental study demonstrates the synthesis of functionalized pyrrolidone carboxylates using ethyl acrylate, highlighting their confirmed three-dimensional structures.
Methyl 4-het(aryl)-3-methoxycarbonylethyl-2-pyrrolidone-3-carboxylates were obtained by the reaction of 4-het(aryl)-3-methoxycarbonylethyl-2-pyrrolidone-3-carboxylates with ethyl acrylate. The structure of the obtained compounds was confirmed by physicochemical methods (1H, 13C{1H} NMR, 1H–13C HMQC, 1H–13C HMBC spectroscopy) and single-crystal X-ray diffraction analysis.
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Ostroglyadov et al. (2026) studied this question.
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