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Clinical review demonstrates individualized management strategies for actinic keratosis based on lesion burden, indicating effective approaches to prevent progression to squamous cell carcinoma.
Actinic keratoses are common premalignant skin lesions caused by chronic exposure to ultraviolet light. Early recognition and effective treatment are key to preventing them from progressing to invasive squamous cell carcinoma. The authors of the article outline an individualized approach for clinicians based on the number of lesions (lesion burden), their surface area (field cancerization), and patient preference.
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Bullock et al. (2026) studied this question.
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