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September 3, 2026Biomicrofluidics

Open/close configurable microfluidic pretreatment device with one-drop anodic stripping voltammetry for on-site heavy metal detection

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Authors

HTHidekatsu TazawaJJJuntao JiangTNTra Huong Nguyen

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Overview

Proof-of-concept study demonstrates microfluidic preconcentration of lead ions for one-drop voltammetry, suggesting a viable route for low-cost on-site heavy metal testing.

Key Points

  • To develop a low-cost, small-volume microfluidic pretreatment platform coupled with one-drop anodic stripping voltammetry for sensitive on-site detection of heavy metal contamination in environmental water.
  • Engineered an open/close configurable microfluidic device utilizing solid-phase extraction with chelating particles.
  • Concentrated a 1.0 mL sample volume down to a single 20 μL droplet to isolate analytes and eliminate matrix impurities.
  • Validated the proof-of-concept platform using Pb2+ ions as the target analyte with screen-printed electrochemical electrodes.
  • Achieved up to a ~50-fold preconcentration factor by reducing 1.0 mL sample volumes to 20 μL.
  • Lowered operational costs by reducing the volume of expensive chelating particles required for sample preparation.
  • Successfully purified Pb2+ from impure solutions, establishing a clean proof-of-concept sample matrix suitable for anodic stripping voltammetry.

Cite This Study

Tazawa et al. (2026) studied this question.

synapsesocial.com/papers/6a9935f3636c6408cfa7e9c2https://doi.org/10.1063/5.0335892
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