Key result
Advanced maternal age in primigravid women was associated with higher odds of low birth weight compared to women aged 20-34 years, though the finding was not statistically significant (OR 2.045).
Why the study?
The number of women delaying pregnancy is increasing, and advanced maternal age carries an increased risk of complications such as low birth weight.
Does advanced maternal age increase the risk of low birth weight in primigravid births?
Cross-Sectional (n=169)
No
Does advanced maternal age increase the risk of low birth weight in primigravid births?
In a cross-sectional study of 169 primigravid births, advanced maternal age was associated with a non-significant increase in the odds of low birth weight.
Non-significant association in small cross-sectional study does not support practice changes; leaves open whether advanced maternal age raises low birth weight risk.
Background: The number of women who delay pregnancy is increasing. Advanced Maternal Age/ AMA (pregnancies in women aged 35 years or older) have increased risks of complications, such as low birth weight/LBW (up to 1.59 times). The aim of this study is to know the association between AMA with LBW in primigravid births. Subjects and Method: This descriptive and analytical, cross sectional research consists of 169 primigravid births in Atma Jaya Hospital Jakarta, collected with a total sampling method for births between February 2016 to September 2021 meeting inclusion criteria. Independent variable included primigravid maternal age and dependent variable included birth weight. Prematurity was used as a dependent variable and an independent variable in two separate analyses. Characteristics of data are described, and analyses were done with the Fisher’s exact test for the associations between primigravid AMA and LBW, , between primigravid AMA and prematurity, and between primigravid prematurity and LBW Spearman’s correlation test was done for the correlation between primigravid maternal age and birth weight. Results: The proportions of women with higher education and maternal diseases are more elevated in AMA. LBW prevalence is 14.79%. The proportion of LBW is higher in AMA (OR=2.045; CI 95% 0.513 to 8.147), with statistically insignificant association (p=0.253). The correlation between maternal age and birth weight is insignificant (p=0.113). AMA has insignificantly higher odds for prematurity (OR=1.139; CI 95% 0.234 to 5.538; p=0.567). The association between prematurity and LBW is highly significant (OR 49.224; CI 95% 15.470 to 156.621; p<0.001). Conclusion: Primigravid women aged ≥35 years have higher proportions of maternal diseases. Despite being statistically insignificant, AMA has higher odds for LBW. Prematurity is highly asso-ciated with LBW. Further research concerning high-risk maternal age needs to be done to improve women’s and children’s health.
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Junus et al. (2023) conducted a cross-sectional in Primigravid pregnancy (n=169). Advanced maternal age (≥35 years) vs. Maternal age 20-34 years was evaluated on Low birth weight (<2500 g) (OR 2.045, 95% CI 0.513 to 8.147, p=0.253). Advanced maternal age in primigravid women was associated with higher odds of low birth weight compared to women aged 20-34 years, though the finding was not statistically significant (OR 2.045).
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