We describe, for the first time, a patient with both symptomatic acromegaly and Chiari-I malformation. These conditions could coexist by chance alone, but the probability of both presenting simultaneously in a previously healthy man seem quite remote. Alternatively, acromegaly through associated bony and soft tissue enlargement could lead to the development of symptoms from Chiari-I malformation in this patient.
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LeMar et al. (1994) studied this question.