Cerium makes it simple: A simple, efficient, and versatile CC bond-forming method for the direct transformation of secondary amides into ketones by Tf2O-mediated deaminative alkylation with organocerium reagents is described. A wide variety of ketones, including α,β-unsaturated ketones, β-chloroenones, diaryl ketones, and ynones, were synthesized by using this method.
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Xiao et al. (2012) studied this question.
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