Answers are grounded in this paper and cite their sources.
An iron-catalyzed regio- and stereoselective addition of acid chlorides to alkynes has been described. The reaction utilizes an inexpensive iron catalyst system and it is suitable for the formation of a variety of bifunctional molecules. This is an inexpensive, regio-, stereoselective and atom-economical approach to beta-chloro-alpha,beta-unsaturated ketones from simple and readily available starting materials.
No takes yet. Share an insight, caveat, or question.
Wang et al. (2010) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: