Pharmacognosy Magazine,2017,13,49s,s161-s163.DOI:10.4103/0973-1296.203988Published:April 2017Type:Letter to the editorAuthors:Biji T Kurien, Hiroyuki Matsumoto, and R Hal Scofield Author(s) affiliations:Biji T Kurien1, Hiroyuki Matsumoto2, R Hal Scofield1 1Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK; Department of Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK; Department of Veterans Affairs, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA 2Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Clinical Proteomics and Gene Therapy Laboratory, Kurume University School of Medicine, Fukuoka, Japan Abstract:Sir, Commercial curcumin contains pure curcumin, demethoxycurcumin, and bisdemethoxycurcumin (77%, 17%, 3%, respectively) of which only demethoxycurcumin is soluble in water at 25ο C [Figure 1]. However, when solubilized with heat, all three curcuminoids become solubilized. These results suggest that biological effects of curcumin rendered in humans or animals when administered in powder form are mainly due to demethoxycurcumin. Read More... Keywords:NilView:PDF (342.25 KB)
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