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In order to improve the survival rate of stem cells in therapy after large-scale culture and transplantation into patients, a stem cell culture system simulating continuous fluctuating pressure in vivo was proposed in this paper. The system analogs the human pulse signals by regularly regulating the internal pressure. It provides blood pressure training for the large-scale culture of stem cells in vitro, which can improve the survival rate after stem cell transplantation, so as to elevate the success rate of cell therapy, and finally provide direction for the development of new culture instrument.
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Junning Cui (2021) studied this question.
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