Key result
Surgical resection of a cardiac mass in a 52-year-old woman with beta thalassemia minor revealed a cardiac myxoma with conspicuous foci of extramedullary hematopoiesis.
Case Report (n=1)
This case report describes a rare presentation of a cardiac myxoma containing foci of extramedullary hematopoiesis in a patient with beta thalassemia minor.
Does not change myxoma management; leaves open whether thalassemia predisposes to hematopoietic foci in cardiac tumors.
A 52-year-old woman presented with recurrent episodes of chest pain, shortness of breath, palpitations, and fatigue for three months. Her past medical history was significant for chronic anemia. Physical examination revealed a pansystolic murmur radiating to the left axilla. Her admission workup showed microcytic anemia. Her serum creatinine and iron studies were within normal limits and her hemoglobin electrophoresis pattern was that of beta thalassemia minor. Two-dimensional echocardiography showed a multilobulated mobile mass attached to the mitral annulus at the base of the anterior mitral valve leaflet. The patient underwent surgical resection of the mass. Pathology examination revealed a cardiac myxoma with conspicuous foci of extramedullary hematopoiesis.
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Joukhadar et al. (2009) conducted a case report in Cardiac myxoma with extramedullary hematopoiesis in beta thalassemia minor (n=1). Surgical resection was evaluated. Surgical resection of a cardiac mass in a 52-year-old woman with beta thalassemia minor revealed a cardiac myxoma with conspicuous foci of extramedullary hematopoiesis.
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