Benzimidazoleis an important pharmacophore which was included in several biologically active compounds resulted in the development of several classes of drugs. This review discusses the synthesis of benzimidazole derivatives as a target agents for antidiabeticby different mechanism such as peroxisome proliferator – activated receptor α transcriptional activity, glycosidases receptor, dipeptidyl peptidase IV, glucokinase, human glucagon receptor (hGCGR) antagonist , aldose reductase enzyme and stearoyl- CoA desaturase.
No takes yet. Share an insight, caveat, or question.
Hassan Y. Aboul‐Enein (2015) studied this question.