Key result
Cardiac complications occurred in 33% of SAH patients and were associated with significantly worse functional outcomes on the Barthel Index (P=0.007) and SF-36 (P=0.014) at 3 months.
Why the study?
Do cardiac complications worsen functional outcomes in adult patients with acute subarachnoid hemorrhage?
Observational (n=81)
Do cardiac complications worsen functional outcomes in adult patients with acute subarachnoid hemorrhage?
p-value: p=0.007
Cardiac complications following subarachnoid hemorrhage are common and negatively impact functional outcomes and quality of life for up to 6 months.
May warrant closer cardiac monitoring in SAH; leaves open whether targeted intervention improves recovery.
OBJECTIVES: To determine the impact of cardiac complications (CdCs) on outcomes in patients with acute subarachnoid hemorrhage (SAH). PATIENTS AND METHODS: Eighty-one adult aneurysmal SAH patients with a fisher grade >1 and/or a Hunt and Hess grade >2 were recruited for this study. CdCs were defined as electrocardiogram (ECG) changes, myocardial necrosis, arrythmias, or pulmonary edema. Outcomes were assessed at 3, 6 and 12 months by telephone interview using the Modified Rankin Scale (MRS), Glasgow Outcome Scale (GOS), Barthel Index and Medical Outcome study Short Form-36 (SF-36). RESULTS: The CdCs occurred in 33% of patients. The most common CdCs were arrythmias and pulmonary edema (30%). There was no significant difference in mortality between the two groups. At 3 months there was a significant difference in the Barthel (P = 0.007) and the SF-36 (P = 0.014) with trends in the GOS (P = 0.049) and the MRS (P = 0.063). At 6 months a significant difference remained in the SF-36 (P = 0.028) and a trend in the Barthel (P = 0.069). CONCLUSION: Results show that CdCs may negatively impact outcomes in SAH patients up to 6 months following hemorrhage.
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Crago et al. (2004) conducted an observational in acute subarachnoid hemorrhage (SAH) (n=81). Cardiac complications vs. No cardiac complications was evaluated on Functional outcomes assessed by Modified Rankin Scale, Glasgow Outcome Scale, Barthel Index, and SF-36 at 3, 6, and 12 months (p=0.007). Cardiac complications occurred in 33% of SAH patients and were associated with significantly worse functional outcomes on the Barthel Index (P=0.007) and SF-36 (P=0.014) at 3 months.
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