Key result
Open abdominal aortic aneurysm repair in the EVAR era was associated with higher complication rates compared to the pre-EVAR era (43.5% vs 23.7%, P=0.025).
Why the study?
Do outcomes and indications for open abdominal aortic aneurysm repair differ between the EVAR and pre-EVAR eras?
Cohort
Do outcomes and indications for open abdominal aortic aneurysm repair differ between the EVAR and pre-EVAR eras?
Absolute Event Rate: 43.5% vs 23.7%
p-value: p=0.025
Patients undergoing open AAA repair in the EVAR era have more comorbidities and higher complication rates than in the pre-EVAR era, though mortality remains similar.
Open repair now reserved for higher-comorbidity patients; leaves open whether selection or era factors drive complications.
The indications for open abdominal aortic aneurysm (AAA) repair have changed with the development of endovascular techniques. The purpose of this study is to clarify the indications and outcomes for open repair since endovascular aneurysm repair (EVAR) and to compare contemporary AAA repair with the pre-EVAR era. Patients undergoing open AAA repair were identified; the demographics, outcomes, and indications for open repair were reviewed. Outcomes were compared based on indication for open repair in the EVAR era and between the pre-EVAR and EVAR eras. Open indications in the EVAR era included: age younger than 65 years with minimal comorbidities (AGE, n = 24 [9.8%]), unfavorable anatomy (ANAT, n = 146 [59.3%]), aortoiliac occlusive disease (AIOD, n = 38 [15.4%]), and miscellaneous (OTHER, n = 38 [15.4%]). Mortality (30-day and 5-year) was affected by indication: AGE = 0 and 0 per cent, ANAT = 4.1 and 49.7 per cent, AIOD = 13.5 and 32.3 per cent, and OTHER = 5.3 and 41.8 per cent. Age, sex, race, coronary artery disease, and peripheral artery disease were similar between the pre-EVAR and EVAR eras. EVAR-era patients had more diabetes mellitus, hypertension, and hyperlipidemia and longer operative time. Mortality was not different, but complication rates were lower in the pre-EVAR era (23.7 vs 43.5%, P = 0.025). Patients undergoing open AAA repair in the EVAR era have more comorbidities, longer operative times, and more complications. Outcomes for EVAR-era patients are affected by the indication for open repair. A preference for open repair in younger patients with minimal comorbidities is justified.
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Joels et al. (2009) conducted a cohort in Abdominal aortic aneurysm. Open AAA repair in the EVAR era vs. Open AAA repair in the pre-EVAR era was evaluated on Complication rates (p=0.025). Open abdominal aortic aneurysm repair in the EVAR era was associated with higher complication rates compared to the pre-EVAR era (43.5% vs 23.7%, P=0.025).
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