Human Serum Transfusions

Moon1states that shock is "a circulatory deficiency, not cardiac or vasomotor in origin." One of the fundamental requirements in combating shock is restoration and maintenance of adequate volume of the circulating blood. Whether shock is primary or secondary, whether due to hemorrhage, trauma or toxic substances, it is generally believed that there is a resultant diminished circulating blood volume and decreased peripheral blood flow. In the presence of dilated and more permeable capillaries, there is progressive blood stasis and subsequent loss of plasma into the tissue spaces. Thus the oxygen supply to the tissues is greatly curtailed. This course of events is progressive unless interrupted. One means of interrupting this sequence is to administer sufficient fluid to restore adequate circulating volume and improve the rate of blood flow. Furthermore, it is imperative that the vicious circle of progressively diminishing blood volume and blood flow and tissue anoxia should