Concentrated Human Blood Serum as a Diuretic in Nephrosis

In July 1938 Aldrich, Stokes, Killingsworth and McGuinness reported the results from treatment of nine patients with pure lipoid nephrosis by intravenous injection of concentrated pooled human serum. In this paper it was shown that, while some of the responses were spectacular and apparently curative, others were disappointing. It is our purpose in this paper to record further experiences with seven additional patients and to tabulate the results not only for these patients but also for the previously recorded nine. In this way it is hoped that some more definite indications for using this method may be found. We are including all the patients with pure nephrosis whom we have seen during the intervening period and in addition are tabulating two additional case reports furnished by Dr. Joseph Stokes Jr., of Philadelphia. Treatment with the serum was instituted as soon as feasible in every case. An initial dose of from