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The nature and the origin of a supernumerary marker chromosome in a mentally retarded boy were determined by various staining techniques on metaphase chromosomes and by GBG high resolution technique. The karyotype was found to be 47,XY, + inv dup(15) (pter----q13: :q13----pter) and the supernumerary chromosome was of maternal origin.
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Joe J. Hoo (1986) studied this question.
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