Answers are grounded in this paper and cite their sources.
We present 16 cases, 10 de novo and 6 familial, in which extra structurally abnormal chromosomes (ESACs) were diagnosed prenatally and identified by fluorescence in situ hybridization (FISH) studies with follow up from birth. We review the literature on prenatally diagnosed ESACs arising de novo and suggest a management protocol for these cases.
No takes yet. Share an insight, caveat, or question.
Hastings et al. (1999) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: