Determination Methods for Biologically Active Compounds by Ultra-Performance Liquid Chromatography Coupled with Mass Spectrometry: Application to the Analyses of Pharmaceuticals, Foods, Plants, Environments, Metabonomics, and Metabolomics

This review summarizes the determination methods for biologically active compounds, such as pharmaceuticals, agrochemicals, and biogenic amines, by ultra-performance liquid chromatography coupled with mass spectrometry. The typical applications using the method are also described in this study, together with the characteristics of the methods.