Cross-Reactivity Using Chimeric Trypanosoma cruzi Antigens: Diagnostic Performance in Settings Where Chagas Disease and American Cutaneous or Visceral Leishmaniasis Are Coendemic

Ramona Tavares Daltro; Leonardo Maia Leony; Natália Erdens Maron Freitas; Ângelo Antônio Oliveira Silva; Emily Ferreira Santos; Rodrigo Pimenta Del-Rei; Maria Edileuza Felinto de Brito; Sinval Pinto Brandão-Filho; Yara M. Gomes; Marcelo Sousa Silva; Silvia Donato; Selma M. B. Jerônimo; Gloria Regina de Góis Monteiro; Lucas P. Carvalho; Andréa Magalhães; Nilson Ivo Tonin Zanchin; Paola Alejandra Fiorani Celedón; Fred Luciano Neves Santos

doi:10.1128/jcm.00762-19

Ask about this paper

Answers are grounded in this paper and cite their sources.

Abstract

Chimeric T. cruzi antigens have been proposed as a diagnostic tool for chronic Chagas disease (CD) in both settings where Chagas disease is endemic and those where it is not endemic. Antibody response varies in accordance to each T. cruzi strain, presenting challenges to the use of antigens lacking demonstrated cross-reactivity with Leishmania spp.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Daltro et al. (2019) studied this question.

synapsesocial.com/papers/6a9973dfaabe11e629a5edfb https://doi.org/10.1128/jcm.00762-19

View Full Paper

Ask AI

Bookmark

Share

Cross-Reactivity Using Chimeric Trypanosoma cruzi Antigens: Diagnostic Performance in Settings Where Chagas Disease and American Cutaneous or Visceral Leishmaniasis Are Coendemic

Ask about this paper

Abstract

Discussion

Cite This Study

Cross-Reactivity Using Chimeric Trypanosoma cruzi Antigens: Diagnostic Performance in Settings Where Chagas Disease and American Cutaneous or Visceral Leishmaniasis Are Coendemic

Ask about this paper

Abstract

Discussion

Cite This Study

Keep reading

Keep reading