Key result
Treatment with transplant nephrectomy, discontinuation of immunosuppression, and immunostimulation with pegylated interferon-α-2a resulted in complete remission for 3 years in a patient with renal allograft hemangiosarcoma.
Case Report (n=1)
Reports a rare case of primary metastasizing hemangiosarcoma in a renal allograft successfully treated with nephrectomy, immunosuppression withdrawal, and pegylated interferon-α-2a.
May guide management of rare renal allograft hemangiosarcoma; hypothesis-generating and requires validation before wider use.
Hemangiosarcomas are rare tumors of endothelial cell origin. To date, only 20 cases of hemangiosarcoma have been described after renal transplantation, occurring mostly in the skin or in a dialysis fistula. We report a primary metastasizing hemangiosarcoma arising from a renal allograft. The patient was treated with transplant nephrectomy, discontinuation of immunosuppression, and immunostimulation with pegylated interferon-α-2a and has now been in complete remission for 3 years.
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Kuntzen et al. (2014) conducted a case report in Primary metastasizing hemangiosarcoma arising from a renal allograft (n=1). Transplant nephrectomy, discontinuation of immunosuppression, and immunostimulation with pegylated interferon-α-2a was evaluated on Complete remission. Treatment with transplant nephrectomy, discontinuation of immunosuppression, and immunostimulation with pegylated interferon-α-2a resulted in complete remission for 3 years in a patient with renal allograft hemangiosarcoma.
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