A Histological Study of the Hepatic and Renal Effects of Subchronic Low Dose Oral Monosodium Glutamate in Swiss Albino Mice

Aim: Earlier studies have shown that exposure to monosodium glutamate (MSG) in large doses during the neonatal period may result in steatohepatitis and evidence of pre neoplastic changes in the liver. However, the effect of low dose, chronic oral MSG intake on the histology of the liver and kidneys have not been addressed to date, this study was designed to ascertain if MSG consumption at these doses is associated with histological evidence of hepatic or renal injuries. Study Design: Experimental study.