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January 1, 1995The Journal of AntibioticsOpen Access

Structure Determination of Ribosylated Rifampicin and Its Derivative: New Inactivated Metabolites of Rifampicin by Mycobacterial Strains.

Naoko Morisaki Hisayoshi Kobayashi Shigeo Iwasaki Kazuo Furihata Eric R. Dabbs Katsukiyo Yazawa Yuzuru Mikami

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Abstract

Rifampicin (I) was converted into two inactivated products RIP-Ma and RIP-Mb by Mycobacterium smegmatis DSM43756. MS, NMR and chromatographic analysis showed the compounds to be 3-formyl-23-[O-(alpha-D-ribofuranosyl)]rifamycin SV (6) and 23-[O-(alpha-D-ribofuranosyl)]rifampicin (7), respectively.

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Morisaki et al. (1995) studied this question.

synapsesocial.com/papers/6a99868b5b560c378c56c819 https://doi.org/10.7164/antibiotics.48.1299

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